Those who develop gout have an increased risk of cancer by 50 percent, with prostate cancer the most common amongst this group. This as per a North American Young Rheumatology Investigator Forum event, with presenter Patricia Kachur MD.
Hello reported that Kachur told attendees at the event that while uric acid can work as a systemic antioxidant within decreased levels, research has indicated that heighted serum uric acid levels can enhance inflammation, which leads to cancer. She went on to note that across the U.S.
, the most common inflammatory illness is categorized by hyperuricemia. It occurs most in men, and is linked to diabetes, hypertension, and obesity. Kachur stated that gout’s prevalence worldwide is increasing, and in the past few years the links between the condition, along with hyperuricemia and cancer, has created a spark for research.
To learn more about a potential link between cancer, Kachur and colleagues launched a study that used Health and Nutrition Examination Survey (NHANES).
Conducted by the National Center for Health Statistics and the Centers for Disease Control and Prevention (CDC), the survey had over 11,200 participants within the general population that were polled between 2011-2014. Individuals were asked to partake laboratory studies, a physical exam, as well as complete a survey. Answers were compiled via a data analysis system, SAS software version 9.4.
As per Kachur, the analysis suggested that those with gout had 50 percent more of a risk to develop a malignancy, with prostate cancer the most common form of this when it came to gout sufferers (a rate of 25 percent). Cancer conditions that followed prostate included colon, breast, and cervix, all having a rate of 8.4 percent. Kachur also stated those surveyed that had rheumatoid arthritis as seemed to have an enhanced risk for developing cancer.
Kachur added that despite the limitations within the study, the team’s findings linked with that of another, as international research has also suggested a correlation between cancer and gout.
Kachur believes more research is needed, with a future focus on these gout patients to review what types of cancers these individuals develop, and the timing around them.
The findings could help when it comes to earlier detection and screening options, potentially saving lives and helping lift the financial and emotional burden cancer has on the public and healthcare facilities.